Further application of 1-bromo-3,5-dimethyladamantane in the future market
2023/8/4
1-Bromo-3,5-dimethyladamantane is an intermediate in organic synthesis and pharmaceutical synthesis, which can be used in laboratory research and pharmaceutical synthesis, and can also be used as an intermediate of memantine.
In the acetonitrile method for the preparation of memantine hydrochloride, 1-bromo-3,5-dimethyladamantane plays a vital role as a raw material.
The method is to react 1-bromo-3,5-dimethyladamantane and acetonitrile under the action of concentrated sulfuric acid to obtain 1-acetylamino-3,5-dimethyladamantane, 1-acetylamino- 3,5-Dimethyladamantane is hydrolyzed under alkaline conditions to obtain 1-amino-3,5-dimethyladamantane, and 1-amino-3,5-dimethyladamantane is acidified with hydrochloric acid to form a salt Diamond crude product, and then recrystallize the crude product to obtain fine product.
As a drug for the treatment of Alzheimer's disease, memantine hydrochloride has broad economic and social benefits, which has led to the further development of the intermediate 1-bromo-3,5-dimethyladamantane.
Nanjing Tengxiang, as an excellent enterprise specializing in the R&D, production, sales and information of pharmaceutical chemical intermediates, can start from the product itself, optimize and perfect the technology, and use the understanding of 1-bromo-3,5-dimethyladamantane , Expand the scope of application of the product and increase the value of the product.
It is believed that with the acceleration of the aging society, the clinical research and synthesis process research of memantine hydrochloride will be further deepened, and 1-bromo-3,5-dimethyladamantane will also lead to a new round of development trend.
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